Abstract
Afferent fibers ending in nerve end neuromas in rats generate a substantial ectopic discharge and are sensitive to light pressure and to circulating adrenaline. Treatment of the nerve with colchicine or vinblastine at the time of the nerve section resulted in a dose-dependent reduction in the extent of this discharge. Such treatment also reduced neuroma discharge that had already gotten underway.
Original language | English |
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Pages (from-to) | 73-85 |
Number of pages | 13 |
Journal | Pain |
Volume | 16 |
Issue number | 1 |
DOIs | |
State | Published - May 1983 |