Backbone cyclic peptide inhibitors of protein kinase B (PKB/Akt)

Keyphrases

• Cyclic Peptide 100%
• Cyclization 100%
• Peptide Inhibitor 100%
• Protein Kinase Inhibitors 100%
• Cyclic Peptoids 100%
• Pharmacological Properties 100%
• Protein Kinase B (PKB)/Akt 100%
• Linear Peptide 50%
• N-terminus 50%
• Cancer Types 50%
• Chemical Modification 50%
• Mitogen-activated Protein Kinase 50%
• Urea 50%
• Peptide-based 50%
• Catalytic Domain 50%
• Cyclic Peptide Library 50%
• Ring Width 50%
• Novel Molecules 50%
• Structure-activity Relationship Studies 50%
• Backbone Amide 50%
• Activity Trends 50%
• Extensive Structure 50%
• Substrate Binding Site 50%
• Specific Substrate 50%
• Surface Mapping 50%
• Akt Kinase 50%

Biochemistry, Genetics and Molecular Biology

• Protein Kinase B 100%
• Cyclic Peptide 100%
• N-Terminus 25%
• Binding Site 25%
• Phosphotransferase 25%
• Kinase 25%
• Structure Activity Relation 25%
• Peptide Library 25%
• Enzyme Active Site 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Cyclopeptide 100%
• Protein Kinase B 100%
• Malignant Neoplasm 25%
• Carboxamide 25%
• Phosphotransferase 25%
• Structure Activity Relationship 25%
• Binding Site 25%
• Protein Kinase B Inhibitor 25%