Bacterial mimics of eukaryotic GTPase-activating proteins (GAPs)

Yael Litvak, Zvi Selinger*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

12 Scopus citations

Abstract

Bacterial GTPase-activating proteins (GAPs) subvert their host's eukaryotic Rho GTPases to their own advantage. Studies of bacterial GAPs extend our understanding of the action of eukaryotic GAPs, provide new tools for studies of cytoskeletal dynamics and offer new targets for anti-bacterial drugs.

Original languageEnglish
Pages (from-to)628-631
Number of pages4
JournalTrends in Biochemical Sciences
Volume28
Issue number12
DOIs
StatePublished - Dec 2003

Bibliographical note

Funding Information:
We thank Roger Kornberg for stimulatory discussion and helpful comments. This work was supported by grants from NIH (EY-03529), the Israel Science Foundation and the Minerva Foundation.

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