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Balancing needs and means: The dilemma of the β-cell in the modern world
G. Leibowitz
, N. Kaiser, E. Cerasi
*
*
Corresponding author for this work
Research output
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Article
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peer-review
13
Scopus citations
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Keyphrases
Cell Function
100%
Mammalian Target of Rapamycin (mTOR)
100%
Type 2 Diabetes Mellitus (T2DM)
100%
Modernity
100%
Balancing Needs
100%
Insulin Resistance
75%
Insulin
50%
Impaired Glucose Tolerance
50%
Disease Severity
25%
Pathophysiology
25%
Adaptation
25%
Cell Death
25%
Rapamycin
25%
Beneficial Effects
25%
Increased Incidence
25%
Deleterious Effects
25%
Diabetes
25%
Psammomys Obesus
25%
Adaptive Capacity
25%
Metabolic Microenvironment
25%
Endoplasmic Reticulum Stress (ER stress)
25%
High Glucose
25%
Cell Apoptosis
25%
Functional Capacity
25%
Severe Impairment
25%
Diabetogenic
25%
Adaptive Rate
25%
Lower End
25%
Insulin Response
25%
Nutrient Intake
25%
Cell Progression
25%
Glucolipotoxicity
25%
Type 1 Diabetic
25%
Blood Glucose Control
25%
High FFA
25%
Tolerance Type
25%
Acquired Factors
25%
Normal Variation
25%
Diabetes Model
25%
Medicine and Dentistry
Cell Function
100%
Maturity Onset Diabetes of the Young
100%
Insulin Resistance
75%
Disease
50%
Diabetes
50%
Impaired Glucose Tolerance
50%
Mechanistic Target of Rapamycin
50%
In Vitro
25%
Programmed Cell Death
25%
Prospective Study
25%
Diabetes Mellitus
25%
Cell Death
25%
Pathophysiology
25%
Endoplasmic Reticulum Stress
25%
Fatty Acid
25%
Mammalian Target of Rapamycin Complex 1
25%
Rapamycin
25%
Lipotoxicity
25%
Reduced Nicotinamide Adenine Dinucleotide Dehydrogenase (Ubiquinone)
25%
Insulin Response
25%
Nutrient Intake
25%
Blood Glucose Monitoring
25%
Agricultural and Biological Sciences
Insulin Resistance
100%
Impaired Glucose Tolerance
66%
Mechanistic Target of Rapamycin
66%
Programmed Cell Death
33%
Endoplasmic reticulum
33%
Psammomys obesus
33%
Nutrient Intake
33%
Prospective Study
33%
Blood Glucose Monitoring
33%
Lipotoxicity
33%
Fatty Acids
33%
Cell Death
33%
NADH Dehydrogenase (Ubiquinone)
33%
Biochemistry, Genetics and Molecular Biology
Cell Function
100%
Insulin Resistance
75%
Mechanistic Target of Rapamycin
50%
Impaired Glucose Tolerance
50%
Cell Death
25%
Endoplasmic Reticulum Stress
25%
Psammomys obesus
25%
Prospective Study
25%
Mammalian Target of Rapamycin Complex 1
25%
Lipotoxicity
25%
Insulin Response
25%
Blood Glucose Monitoring
25%
Immunology and Microbiology
Cell Function
100%
Sirolimus
75%
Insulin Resistance
75%
Glucose Blood Level
25%
Cell Death
25%
Endoplasmic Reticulum Stress
25%
Psammomys obesus
25%
Mammalian Target of Rapamycin Complex 1
25%
Insulin Response
25%