Barbiturate narcosis and estrogen levels in women

A. Bergman, D. Niv, M. P. David, J. Yanai

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Pregnant women with high estrogen levels were more sensitive to barbiturate-induced narcosis and hypothermia than nonpregnant and postmenopausal women. Within each group, there was a negative correlation between estrogen levels and decreased sensitivity to barbiturates. It appears that estrogen alters resistance to barbiturates through its effect on the activity of dopamine receptors.

Original languageEnglish
Pages (from-to)167-171
Number of pages5
JournalGynecologic and Obstetric Investigation
Volume23
Issue number3
DOIs
StatePublished - 1987
Externally publishedYes

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