Barbiturate narcosis and estrogen levels in women

A. Bergman; D. Niv; M. P. David; J. Yanai

doi:10.1159/000298857

Barbiturate narcosis and estrogen levels in women

A. Bergman
, D. Niv
, M. P. David
, J. Yanai

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Pregnant women with high estrogen levels were more sensitive to barbiturate-induced narcosis and hypothermia than nonpregnant and postmenopausal women. Within each group, there was a negative correlation between estrogen levels and decreased sensitivity to barbiturates. It appears that estrogen alters resistance to barbiturates through its effect on the activity of dopamine receptors.

Original language	English
Pages (from-to)	167-171
Number of pages	5
Journal	Gynecologic and Obstetric Investigation
Volume	23
Issue number	3
DOIs	https://doi.org/10.1159/000298857
State	Published - 1987
Externally published	Yes

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title = "Barbiturate narcosis and estrogen levels in women",

abstract = "Pregnant women with high estrogen levels were more sensitive to barbiturate-induced narcosis and hypothermia than nonpregnant and postmenopausal women. Within each group, there was a negative correlation between estrogen levels and decreased sensitivity to barbiturates. It appears that estrogen alters resistance to barbiturates through its effect on the activity of dopamine receptors.",

author = "A. Bergman and D. Niv and David, \{M. P.\} and J. Yanai",

year = "1987",

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journal = "Gynecologic and Obstetric Investigation",

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T1 - Barbiturate narcosis and estrogen levels in women

AU - Bergman, A.

AU - Niv, D.

AU - David, M. P.

AU - Yanai, J.

PY - 1987

Y1 - 1987

N2 - Pregnant women with high estrogen levels were more sensitive to barbiturate-induced narcosis and hypothermia than nonpregnant and postmenopausal women. Within each group, there was a negative correlation between estrogen levels and decreased sensitivity to barbiturates. It appears that estrogen alters resistance to barbiturates through its effect on the activity of dopamine receptors.

AB - Pregnant women with high estrogen levels were more sensitive to barbiturate-induced narcosis and hypothermia than nonpregnant and postmenopausal women. Within each group, there was a negative correlation between estrogen levels and decreased sensitivity to barbiturates. It appears that estrogen alters resistance to barbiturates through its effect on the activity of dopamine receptors.

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DO - 10.1159/000298857

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EP - 171

JO - Gynecologic and Obstetric Investigation

JF - Gynecologic and Obstetric Investigation

IS - 3

ER -

Barbiturate narcosis and estrogen levels in women

Abstract

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