The authors examined the incremental validity of the reaction time (RT) measure beyond that of skin conductance response (SCR) in the detection of concealed information. Participants performed a Stroop-like task in which they named the color of critical and neutral words. Results show that the SCR highly differentiated between the relevant and neutral words. However, the RT demonstrated a significant differentiation only when the critical words denoted personally significant items (e.g., one's own name) and not when they denoted crime-relevant items related to a simulated crime. In both cases, combining the 2 measures yielded no advantage over the use of SCR alone. Thus, although behavioral measures may differentiate between relevant and neutral information in some cases, their practical use is questionable.