TY - JOUR
T1 - Biodegradable polymers
T2 - An update
AU - Shikanov, Ariella
AU - Kumar, Neeraj
AU - Domb, Abraham J.
PY - 2005
Y1 - 2005
N2 - The use of polymeric materials for the administration of pharmaceuticals, and as biomedical devices has increased dramatically. This review focuses on synthetic biodegradable polymers of current interest for medical use, based on ester and anhydride bonds. Special attention is given to factors affecting biodegradation, including: polymer structure, morphology, molecular weight, radiation, and chemical treatment, as well as the effects of drugs and plasticizers added to the polymer mass. The toxicity and biocompatibility of the polymers and their current and future applications in medicine are also briefly reviewed.
AB - The use of polymeric materials for the administration of pharmaceuticals, and as biomedical devices has increased dramatically. This review focuses on synthetic biodegradable polymers of current interest for medical use, based on ester and anhydride bonds. Special attention is given to factors affecting biodegradation, including: polymer structure, morphology, molecular weight, radiation, and chemical treatment, as well as the effects of drugs and plasticizers added to the polymer mass. The toxicity and biocompatibility of the polymers and their current and future applications in medicine are also briefly reviewed.
UR - http://www.scopus.com/inward/record.url?scp=27844525056&partnerID=8YFLogxK
U2 - 10.1560/ATQM-MQ02-GLDU-EF6L
DO - 10.1560/ATQM-MQ02-GLDU-EF6L
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AN - SCOPUS:27844525056
SN - 0021-2148
VL - 45
SP - 393
EP - 399
JO - Israel Journal of Chemistry
JF - Israel Journal of Chemistry
IS - 4
ER -