TY - JOUR
T1 - Biogeographical Landscape of the Human Face Skin Microbiome Viewed in High Definition
AU - Brandwein, Michael
AU - Fuks, Garold
AU - Israel, Avigail
AU - Hodak, Emmilia
AU - Sabbah, Fareed
AU - Steinberg, Doron
AU - Bentwich, Zvi
AU - Shental, Noam
AU - Meshner, Shiri
N1 - Publisher Copyright:
© 2021, Medical Journals/Acta D-V. All rights reserved.
PY - 2021/11/24
Y1 - 2021/11/24
N2 - The bacterial community that colonizes the human face imparts physiochemical and physiological effects on the facial skin. These skin-microbe interactions impact dermatological, cosmetic and skincare applications due to the centrality of the human face in daily interactions. However, fine-scale characterization of the human face skin microbiome is lacking. Using 16S rRNA sequencing and 3D cartography, this study plotted and characterized the facial skin microbiome in highdefinition, based on 1,649 samples from 12 individuals. Analysis yielded a number of novel insights, including that of the relative uniformity of skin microbiome composition within skin sites, site localization of certain microbes, and the interpersonal variability of the skin microbiome. The results show that high-resolution topographical mapping of the skin microbiome is a powerful tool for studying the human skin microbiome. Despite a decade of skin microbiome research, there is still much to be discovered.
AB - The bacterial community that colonizes the human face imparts physiochemical and physiological effects on the facial skin. These skin-microbe interactions impact dermatological, cosmetic and skincare applications due to the centrality of the human face in daily interactions. However, fine-scale characterization of the human face skin microbiome is lacking. Using 16S rRNA sequencing and 3D cartography, this study plotted and characterized the facial skin microbiome in highdefinition, based on 1,649 samples from 12 individuals. Analysis yielded a number of novel insights, including that of the relative uniformity of skin microbiome composition within skin sites, site localization of certain microbes, and the interpersonal variability of the skin microbiome. The results show that high-resolution topographical mapping of the skin microbiome is a powerful tool for studying the human skin microbiome. Despite a decade of skin microbiome research, there is still much to be discovered.
KW - 3D cartography
KW - Cutibacterium acnes
KW - Facial microbiome
KW - Skin microbiome
KW - Staphylococcus aureus
KW - Staphylococcus epidermidis
UR - http://www.scopus.com/inward/record.url?scp=85122166499&partnerID=8YFLogxK
U2 - 10.2340/00015555-3929
DO - 10.2340/00015555-3929
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C2 - 34515801
AN - SCOPUS:85122166499
SN - 0001-5555
VL - 101
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
IS - 11
M1 - adv00603
ER -