Abstract
Here, we describe BioInfo3D, a suite of freely available web services for protein structural analysis. The FlexProt method performs flexible structural alignment of protein molecules. FlexProt simultaneously detects the hinge regions and aligns the rigid subparts of the molecules. It does not require an a priori knowledge of the flexible hinge regions. MultiProt and MASS perform simultaneous comparison of multiple protein structures. PatchDock performs prediction of protein-protein and protein-small molecule interactions. The input to all services is either protein PDB codes or protein structures uploaded to the server. All the services are available at http://bioinfo3d.cs.tau.ac.il.
| Original language | English |
|---|---|
| Pages (from-to) | W503-W507 |
| Journal | Nucleic Acids Research |
| Volume | 32 |
| Issue number | WEB SERVER ISS. |
| DOIs | |
| State | Published - 1 Jul 2004 |
| Externally published | Yes |
Bibliographical note
Funding Information:We thank our Structural Bioinformatics Group and the system team at Tel Aviv University. The research of R.N. and H.J.W. in Israel has been supported in part by the Center of Excellence in Geometric Computing and its Applications funded by the Israel Science Foundation (administered by the Israel Academy of Sciences) and by the Tel Aviv University Adams Brain Center. The research of H.J.W. is partially supported by the Hermann Minkowski-Minerva Center for Geometry at Tel Aviv University. This project has been funded in whole or in part with Federal funds from the National Cancer Institute, National Institutes of Health, under contract number NO1-CO-12400. The content of this publication does not necessarily reflect the view or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products or organizations imply endorsement by the US Government.