Bioinspired design of nanocages by self-assembling triskelion peptide elements

Surajit Ghosh*, Meital Reches, Ehud Gazit, Sandeep Verma

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

138 Scopus citations


Winning the three-legged race: Rapid self-organization of a tripodal aromatic dipeptide conjugate on a tris(2-amino-ethyl)amine scaffold leads to a vesicular morphology (upper image). The structures can trap a fluorescent dye (lower image) and release it upon acidification, suggesting the use of such stimuli-responsive materials as potential delivery vehicles. (Figure Presented).

Original languageAmerican English
Pages (from-to)2002-2004
Number of pages3
JournalAngewandte Chemie - International Edition
Issue number12
StatePublished - 2007
Externally publishedYes


  • Electron microscopy
  • Fluorescence
  • Peptides
  • Self-assembly
  • Vesicles


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