Bioinspired design of nanocages by self-assembling triskelion peptide elements

Surajit Ghosh; Meital Reches; Ehud Gazit; Sandeep Verma

doi:10.1002/anie.200604383

Bioinspired design of nanocages by self-assembling triskelion peptide elements

Surajit Ghosh^*, Meital Reches, Ehud Gazit, Sandeep Verma

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

139 Scopus citations

Abstract

Winning the three-legged race: Rapid self-organization of a tripodal aromatic dipeptide conjugate on a tris(2-amino-ethyl)amine scaffold leads to a vesicular morphology (upper image). The structures can trap a fluorescent dye (lower image) and release it upon acidification, suggesting the use of such stimuli-responsive materials as potential delivery vehicles. (Figure Presented).

Original language	English
Pages (from-to)	2002-2004
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	12
DOIs	https://doi.org/10.1002/anie.200604383
State	Published - 2007
Externally published	Yes

Keywords

Electron microscopy
Fluorescence
Peptides
Self-assembly
Vesicles

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10.1002/anie.200604383

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KW - Electron microscopy

KW - Fluorescence

KW - Peptides

KW - Self-assembly

KW - Vesicles

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Bioinspired design of nanocages by self-assembling triskelion peptide elements

Abstract

Keywords

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