Biological function of prokineticins

Q. Y. Zhou*, R. Meidan

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

14 Scopus citations

Abstract

Secreted peptides have been implicated in diverse physiological functions. Prokineticins are a pair of regulatory peptides that signal through two highly homologous G protein-coupled receptors. Prokineticins possess a unique structural motif of five disulfide bonds and conserved N-terminal stretches. Diverse biological functions, ranging from development to adult physiology, have been attributed to prokineticins. Herein we provide an overview of current knowledge of this interesting pair of regulatory peptides.

Original languageEnglish
Title of host publicationOrphan G Protein-Coupled Receptors and Novel Neuropeptides
EditorsOlivier Civelli, Qun-Yong Zhou
Pages181-199
Number of pages19
DOIs
StatePublished - 2008

Publication series

NameResults and Problems in Cell Differentiation
Volume46
ISSN (Print)0080-1844
ISSN (Electronic)1861-0412

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