Biosensing and probing of intracellular metabolic pathways by NADH-sensitive quantum dots

Ronit Freeman*, Ron Gill, Itzhak Shweky, Moshe Kotler, Uri Banin, Itamar Willner

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

122 Scopus citations

Abstract

(Figure Presented) On the blue Nile: NAD(P)H-sensitive Nile Blue functionalized CdSe/ZnS quantum dots have been developed for the optical sensing of biocatalytic processes involving NAD+-dependent enzymes and the screening of anticancer drugs by monitoring intracellular metabolism (see picture).

Original languageAmerican English
Pages (from-to)309-313
Number of pages5
JournalAngewandte Chemie - International Edition
Volume48
Issue number2
DOIs
StatePublished - 2 Jan 2009

Keywords

  • Biosensors
  • Enzymes
  • Nanobiotechnology
  • Nanoparticles
  • Quantum dots

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