Brain plasticity-based therapeutics

Michael M. Merzenich, Thomas M. Van Vleet, Mor Nahum

Research output: Contribution to journalReview articlepeer-review

131 Scopus citations

Abstract

The primary objective of this review article is to summarize how the neuroscience of brain plasticity, exploiting new findings in fundamental, integrative and cognitive neuroscience, is changing the therapeutic landscape for professional communities addressing brain-based disorders and disease. After considering the neurological bases of training-driven neuroplasticity, we shall describe how this neuroscience-guided perspective distinguishes this new approach from (a) the more-behavioral, traditional clinical strategies of professional therapy practitioners, and (b) an even more widely applied pharmaceutical treatment model for neurological and psychiatric treatment domains. With that background, we shall argue that neuroplasticity-based treatments will be an important part of future best-treatment practices in neurological and psychiatric medicine.

Original languageAmerican English
Article number385
JournalFrontiers in Human Neuroscience
Volume8
Issue numberJUNE
DOIs
StatePublished - 27 Jun 2014
Externally publishedYes

Keywords

  • Aging
  • Brain plasticity
  • Computerized training
  • Hemispatial neglect
  • Neuroplasticity
  • Schizophrenia

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