Abstract
The plasmid-encoded quinolone resistance gene qnrA confers low-level quinolone resistance, facilitating selection of higher-level resistance. Epidemiologic surveys for qnrA were extended to isolates of Enterobacter spp. and to quinolone-susceptible Enterobacteriaceae. Two (10%) of 20 ceftazidime-resistant quinolone-susceptible Klebsiella pneumoniae strains carried the gene, as did 12 (17%) of 71 ceftazidime-resistant Enterobacter strains from across the United States. One of these Enterobacter isolates was quinolone susceptible. Thus, qnrA is present in quinolone-resistant and quinolone-susceptible Enterobacter and Klebsiella strains in the United States.
Original language | American English |
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Pages (from-to) | 3001-3003 |
Number of pages | 3 |
Journal | Antimicrobial Agents and Chemotherapy |
Volume | 49 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2005 |
Externally published | Yes |