TY - JOUR
T1 - Bronchiolitis Due to RSV and HMPV—Epidemiology, Clinical Course, and Prognosis
T2 - Experience of a Single Tertiary Center
AU - Azar, Bar
AU - Hashavya, Saar
AU - Ohana Sarna Cahan, Lea
AU - Reif, Shimon
AU - Gross, Itai
N1 - Publisher Copyright:
© The Author(s) 2023.
PY - 2023/10
Y1 - 2023/10
N2 - Acute bronchiolitis is a leading cause of hospitalization in infants. In this retrospective study, 645 patients with acute bronchiolitis diagnosed as respiratory syncytial virus (RSV; n = 538) or human metapneumovirus (HMPV; n = 107) were compared in terms of demographic, clinical, and laboratory findings. The HMPV patients presented later in the winter, were older (20 vs 7.55 months; P <.001)), had higher levels of C-reactive protein (4.55 vs 3.03 mg/dL; P =.007), and a higher prevalence of complications (43.9% vs 32.7%; P =.03). This study highlights the similarities and differences between these 2 common respiratory viral pathogens and shows that HMPV has a slightly more severe disease course than RSV. These findings can help guide approaches to these 2 common viruses that cause bronchiolitis.
AB - Acute bronchiolitis is a leading cause of hospitalization in infants. In this retrospective study, 645 patients with acute bronchiolitis diagnosed as respiratory syncytial virus (RSV; n = 538) or human metapneumovirus (HMPV; n = 107) were compared in terms of demographic, clinical, and laboratory findings. The HMPV patients presented later in the winter, were older (20 vs 7.55 months; P <.001)), had higher levels of C-reactive protein (4.55 vs 3.03 mg/dL; P =.007), and a higher prevalence of complications (43.9% vs 32.7%; P =.03). This study highlights the similarities and differences between these 2 common respiratory viral pathogens and shows that HMPV has a slightly more severe disease course than RSV. These findings can help guide approaches to these 2 common viruses that cause bronchiolitis.
KW - bronchiolitis
KW - children
KW - human metapneumovirus
KW - infants
KW - respiratory distress
KW - respiratory syncytial virus
UR - http://www.scopus.com/inward/record.url?scp=85147593251&partnerID=8YFLogxK
U2 - 10.1177/00099228231151401
DO - 10.1177/00099228231151401
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C2 - 36744682
AN - SCOPUS:85147593251
SN - 0009-9228
VL - 62
SP - 1032
EP - 1039
JO - Clinical Pediatrics
JF - Clinical Pediatrics
IS - 9
ER -