Bronchiolitis Due to RSV and HMPV—Epidemiology, Clinical Course, and Prognosis: Experience of a Single Tertiary Center

Bar Azar, Saar Hashavya, Lea Ohana Sarna Cahan, Shimon Reif, Itai Gross*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Acute bronchiolitis is a leading cause of hospitalization in infants. In this retrospective study, 645 patients with acute bronchiolitis diagnosed as respiratory syncytial virus (RSV; n = 538) or human metapneumovirus (HMPV; n = 107) were compared in terms of demographic, clinical, and laboratory findings. The HMPV patients presented later in the winter, were older (20 vs 7.55 months; P <.001)), had higher levels of C-reactive protein (4.55 vs 3.03 mg/dL; P =.007), and a higher prevalence of complications (43.9% vs 32.7%; P =.03). This study highlights the similarities and differences between these 2 common respiratory viral pathogens and shows that HMPV has a slightly more severe disease course than RSV. These findings can help guide approaches to these 2 common viruses that cause bronchiolitis.

Original languageEnglish
Pages (from-to)1032-1039
Number of pages8
JournalClinical Pediatrics
Volume62
Issue number9
DOIs
StatePublished - Oct 2023
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s) 2023.

Keywords

  • bronchiolitis
  • children
  • human metapneumovirus
  • infants
  • respiratory distress
  • respiratory syncytial virus

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