Calcium resorption from bone in a human studied by 41Ca tracing

R. R. Johnson; D. Berkovits; E. Boaretto; Z. Gelbart; S. Ghelberg; O. Meirav; M. Paul; J. Prior; V. Sossi; E. Venczel

doi:10.1016/0168-583X(94)96059-3

Calcium resorption from bone in a human studied by ⁴¹Ca tracing

R. R. Johnson^*
, D. Berkovits
, E. Boaretto
, Z. Gelbart
, S. Ghelberg
, O. Meirav
, M. Paul
, J. Prior
, V. Sossi
, E. Venczel

^*Corresponding author for this work

Racah Institute of Physics

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

We are investigating long- and short-term processes that involve the resorption of the bone calcium in the human body, using accelerator mass spectrometry of ⁴¹Ca (T_{1 2} = 104000 years). The evolution of an injected dose of ⁴¹Ca has been followed over 900 days by measurements in urine and serum. The ⁴¹ Ca/Ca isotopic ratio rapidly decreased after injection and after about 100 days, reached a quasi-steady state of 1.5 × 10^-11. Variations in this level would signal a change in rates of calcium resorption from the bone.

Original language	English
Pages (from-to)	483-488
Number of pages	6
Journal	Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Volume	92
Issue number	1-4
DOIs	https://doi.org/10.1016/0168-583X(94)96059-3
State	Published - 3 Jun 1994

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Johnson, R. R., Berkovits, D., Boaretto, E., Gelbart, Z., Ghelberg, S., Meirav, O., Paul, M., Prior, J., Sossi, V., & Venczel, E. (1994). Calcium resorption from bone in a human studied by ⁴¹Ca tracing. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, 92(1-4), 483-488. https://doi.org/10.1016/0168-583X(94)96059-3

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abstract = "We are investigating long- and short-term processes that involve the resorption of the bone calcium in the human body, using accelerator mass spectrometry of 41Ca (T 1 2 = 104000 years). The evolution of an injected dose of 41Ca has been followed over 900 days by measurements in urine and serum. The 41 Ca/Ca isotopic ratio rapidly decreased after injection and after about 100 days, reached a quasi-steady state of 1.5 × 10-11. Variations in this level would signal a change in rates of calcium resorption from the bone.",

author = "Johnson, \{R. R.\} and D. Berkovits and E. Boaretto and Z. Gelbart and S. Ghelberg and O. Meirav and M. Paul and J. Prior and V. Sossi and E. Venczel",

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doi = "10.1016/0168-583X(94)96059-3",

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Johnson, RR, Berkovits, D, Boaretto, E, Gelbart, Z, Ghelberg, S, Meirav, O, Paul, M, Prior, J, Sossi, V & Venczel, E 1994, 'Calcium resorption from bone in a human studied by ⁴¹Ca tracing', Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, vol. 92, no. 1-4, pp. 483-488. https://doi.org/10.1016/0168-583X(94)96059-3

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T1 - Calcium resorption from bone in a human studied by 41Ca tracing

AU - Johnson, R. R.

AU - Berkovits, D.

AU - Boaretto, E.

AU - Gelbart, Z.

AU - Ghelberg, S.

AU - Meirav, O.

AU - Paul, M.

AU - Prior, J.

AU - Sossi, V.

AU - Venczel, E.

PY - 1994/6/3

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N2 - We are investigating long- and short-term processes that involve the resorption of the bone calcium in the human body, using accelerator mass spectrometry of 41Ca (T 1 2 = 104000 years). The evolution of an injected dose of 41Ca has been followed over 900 days by measurements in urine and serum. The 41 Ca/Ca isotopic ratio rapidly decreased after injection and after about 100 days, reached a quasi-steady state of 1.5 × 10-11. Variations in this level would signal a change in rates of calcium resorption from the bone.

AB - We are investigating long- and short-term processes that involve the resorption of the bone calcium in the human body, using accelerator mass spectrometry of 41Ca (T 1 2 = 104000 years). The evolution of an injected dose of 41Ca has been followed over 900 days by measurements in urine and serum. The 41 Ca/Ca isotopic ratio rapidly decreased after injection and after about 100 days, reached a quasi-steady state of 1.5 × 10-11. Variations in this level would signal a change in rates of calcium resorption from the bone.

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JO - Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms

JF - Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms

IS - 1-4

ER -

Calcium resorption from bone in a human studied by ⁴¹Ca tracing

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