TY - JOUR
T1 - Cannabidiol
T2 - An overview of some pharmacological aspects
AU - Mechoulam, Raphael
AU - Parker, Linda A.
AU - Gallily, Ruth
PY - 2002/11/1
Y1 - 2002/11/1
N2 - Over the past few years, considerable attention has focused on cannabidiol (CBD), a major nonpsychotropic constituent of cannabis. The authors present a review on the chemistry of CBD and discuss the anticonvulsive, antianxiety, antipsychotic, antinausea, and antirheumatoid arthritic properties of CBD. CBD does not bind to the known cannabinoid receptors, and its mechanism of action is yet unknown. It is possible that, in part at least, its effects are due to its recently discovered inhibition of anandamide uptake and hydrolysis and to its antioxidative effect.
AB - Over the past few years, considerable attention has focused on cannabidiol (CBD), a major nonpsychotropic constituent of cannabis. The authors present a review on the chemistry of CBD and discuss the anticonvulsive, antianxiety, antipsychotic, antinausea, and antirheumatoid arthritic properties of CBD. CBD does not bind to the known cannabinoid receptors, and its mechanism of action is yet unknown. It is possible that, in part at least, its effects are due to its recently discovered inhibition of anandamide uptake and hydrolysis and to its antioxidative effect.
UR - http://www.scopus.com/inward/record.url?scp=0036838389&partnerID=8YFLogxK
U2 - 10.1002/j.1552-4604.2002.tb05998.x
DO - 10.1002/j.1552-4604.2002.tb05998.x
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C2 - 12412831
AN - SCOPUS:0036838389
SN - 0091-2700
VL - 42
SP - 11S-19S
JO - Journal of Clinical Pharmacology
JF - Journal of Clinical Pharmacology
IS - 11 SUPPL.
ER -