TY - JOUR
T1 - Capturing cellular machines by systematic screens of protein complexes
AU - Gagneur, Julien
AU - David, Lior
AU - Steinmetz, Lars M.
PY - 2006/8
Y1 - 2006/8
N2 - Two recent studies have provided the most complete screen for protein complexes in yeast to date, in which partners were identified for approximately half of the proteome. A comparison shows that these two datasets are complementary. In addition, one of the analyses points to a modular organization of the cellular protein network. These data will prove useful in defining principles and trends that arise when combining large-scale datasets of different natures, and in deriving properties of protein machines in cellular systems.
AB - Two recent studies have provided the most complete screen for protein complexes in yeast to date, in which partners were identified for approximately half of the proteome. A comparison shows that these two datasets are complementary. In addition, one of the analyses points to a modular organization of the cellular protein network. These data will prove useful in defining principles and trends that arise when combining large-scale datasets of different natures, and in deriving properties of protein machines in cellular systems.
UR - https://www.scopus.com/pages/publications/33746274586
U2 - 10.1016/j.tim.2006.06.002
DO - 10.1016/j.tim.2006.06.002
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.shortsurvey???
C2 - 16782340
AN - SCOPUS:33746274586
SN - 0966-842X
VL - 14
SP - 336
EP - 339
JO - Trends in Microbiology
JF - Trends in Microbiology
IS - 8
ER -