TY - JOUR
T1 - Case report
T2 - Coinfection of leishmania guyanensis and human immunodeficiency virus-acquired immune deficiency syndrome: Report of a case of disseminated cutaneous leishmaniasis in Ecuador
AU - Calvopina, Manuel
AU - Aguirre, Cristina
AU - Cevallos, William
AU - Castillo, Alberto
AU - Abbasi, Ibrahim
AU - Warburg, Alon
N1 - Publisher Copyright:
Copyright © 2017 by The American Society of Tropical Medicine and Hygiene.
PY - 2017
Y1 - 2017
N2 - Reported herein is the first case of Leishmania-human immunodeficiency virus (HIV) coinfection in Ecuador. In Ecuador, HIV infections overlap endemic areas of leishmaniasis. Immunosuppression is a wellestablished risk factor for developing severe disease. This is a severe case of a 32-year-old man presenting with disseminated pleomorphic ulcers, papules, and cutaneous plaque-like lesions over his whole body. Numerous amastigotes were observed in both skin scrapings and biopsies. The sequence of the cytochrome b gene confirmed the presence of Leishmania guyanensis. The patient was treated but failed to respond to meglumine antimoniate and amphotericin B. Six months later, the patient died due to bacterial septic shock.
AB - Reported herein is the first case of Leishmania-human immunodeficiency virus (HIV) coinfection in Ecuador. In Ecuador, HIV infections overlap endemic areas of leishmaniasis. Immunosuppression is a wellestablished risk factor for developing severe disease. This is a severe case of a 32-year-old man presenting with disseminated pleomorphic ulcers, papules, and cutaneous plaque-like lesions over his whole body. Numerous amastigotes were observed in both skin scrapings and biopsies. The sequence of the cytochrome b gene confirmed the presence of Leishmania guyanensis. The patient was treated but failed to respond to meglumine antimoniate and amphotericin B. Six months later, the patient died due to bacterial septic shock.
UR - http://www.scopus.com/inward/record.url?scp=85019170029&partnerID=8YFLogxK
U2 - 10.4269/ajtmh.16-0431
DO - 10.4269/ajtmh.16-0431
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C2 - 28193741
AN - SCOPUS:85019170029
SN - 0002-9637
VL - 96
SP - 1151
EP - 1154
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 5
ER -