Casting metal nanowires within discrete self-assembled peptide nanotubes

Meital Reches, Ehud Gazit*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2229 Scopus citations

Abstract

Tubular nanostructures are suggested to have a wide range of applications in nanotechnology. We report our observation of the self-assembly of a very short peptide, the Alzheimer's β-amyloid diphenylatanine structural motif, into discrete and stiff nanotubes. Reduction of ionic silver within the nanotubes, followed by enzymatic degradation of the peptide backbone, resulted in the production of discrete nanowires with a long persistence length. The same dipeptide building block, made of D-phenylalanine, resulted in the production of enzymatically stable nanotubes.

Original languageAmerican English
Pages (from-to)625-627
Number of pages3
JournalScience
Volume300
Issue number5619
DOIs
StatePublished - 25 Apr 2003
Externally publishedYes

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