CD additivity in trichothecene benzoates: application as a microanalytical method for trichothecene characterization

The additivity relation in A values of split CD curves previously established with pyranose p-bromobenzoates was shown to be valid for p-bromobenzoates of the cage-like trichothecene system (which also possesses a primary hydroxyl group). This suggests that additivity is generally valid even for congested multichromophoric molecules. The relation has been integrated Into a new micro method for trichothecene characterization, which was applied to a new trichothecene from Fusarium sporotrichioides (MC-72083) at a sub- μg level.