TY - JOUR
T1 - Cell substrate adhesiveness in S49 mouse lymphoma
AU - Hochman, Jacob
AU - Katz, Aviva
AU - Levy, Efrat
AU - Eshel, Shmuela
PY - 1980
Y1 - 1980
N2 - A new variant subline was selected from S49 mouse lymphoma cells grown in suspension culture. These cells, designated S49-Adh, demonstrate increased adhesiveness to their substratum. This, in turn, allows them to grow as a monolayer. Once a dense monolayer is formed, daughter cells develop as a suspension borne population while still retaining their substrate adhesiveness. Cell substrate adhesiveness is a stable genetic trait insofar as submitting S49-Adh cells to both extended periods of in vitro cultivation in culture medium, or in vivo selection through passage in nude mice didn't change their substrate-adhesive phenotype.
AB - A new variant subline was selected from S49 mouse lymphoma cells grown in suspension culture. These cells, designated S49-Adh, demonstrate increased adhesiveness to their substratum. This, in turn, allows them to grow as a monolayer. Once a dense monolayer is formed, daughter cells develop as a suspension borne population while still retaining their substrate adhesiveness. Cell substrate adhesiveness is a stable genetic trait insofar as submitting S49-Adh cells to both extended periods of in vitro cultivation in culture medium, or in vivo selection through passage in nude mice didn't change their substrate-adhesive phenotype.
UR - http://www.scopus.com/inward/record.url?scp=0019125867&partnerID=8YFLogxK
U2 - 10.1016/0309-1651(80)90198-8
DO - 10.1016/0309-1651(80)90198-8
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C2 - 7418013
AN - SCOPUS:0019125867
SN - 0309-1651
VL - 4
SP - 953
EP - 959
JO - Cell Biology International Reports
JF - Cell Biology International Reports
IS - 10
ER -
