Cellular interactions of platinum drugs

Ezequiel Wexselblatt; Eylon Yavin; Dan Gibson

doi:10.1016/j.ica.2012.07.013

Cellular interactions of platinum drugs

Ezequiel Wexselblatt, Eylon Yavin, Dan Gibson^*

^*Corresponding author for this work

School of Pharmacy

Research output: Contribution to journal › Review article › peer-review

62 Scopus citations

Abstract

This manuscript represents a critical review of selected topics relating to the cellular interactions of platinum anticancer drugs. The intent is not to provide a comprehensive summary of all the work described in the literature but to raise questions and cast doubts about selected topics regarding the approaches taken towards trying to elucidate the event that happens in cancer cells that were exposed to platinum complexes. The experimental methods used to study the cellular interactions of platinum complexes are reviewed and the significance of the results obtained from such studies is discussed.

Original language	American English
Pages (from-to)	75-83
Number of pages	9
Journal	Inorganica Chimica Acta
Volume	393
DOIs	https://doi.org/10.1016/j.ica.2012.07.013
State	Published - 1 Dec 2012

Bibliographical note

Funding Information:
D.G. thanks the Israel Science Foundation for financial support (Grant 1332/10 ).

Keywords

Cellular interactions
Platinun anti cancer agents

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ica.2012.07.013

Cite this

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title = "Cellular interactions of platinum drugs",

abstract = "This manuscript represents a critical review of selected topics relating to the cellular interactions of platinum anticancer drugs. The intent is not to provide a comprehensive summary of all the work described in the literature but to raise questions and cast doubts about selected topics regarding the approaches taken towards trying to elucidate the event that happens in cancer cells that were exposed to platinum complexes. The experimental methods used to study the cellular interactions of platinum complexes are reviewed and the significance of the results obtained from such studies is discussed.",

keywords = "Cellular interactions, Platinun anti cancer agents",

author = "Ezequiel Wexselblatt and Eylon Yavin and Dan Gibson",

note = "Funding Information: D.G. thanks the Israel Science Foundation for financial support (Grant 1332/10 ). ",

year = "2012",

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language = "American English",

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T1 - Cellular interactions of platinum drugs

AU - Wexselblatt, Ezequiel

AU - Yavin, Eylon

AU - Gibson, Dan

N1 - Funding Information: D.G. thanks the Israel Science Foundation for financial support (Grant 1332/10 ).

PY - 2012/12/1

Y1 - 2012/12/1

N2 - This manuscript represents a critical review of selected topics relating to the cellular interactions of platinum anticancer drugs. The intent is not to provide a comprehensive summary of all the work described in the literature but to raise questions and cast doubts about selected topics regarding the approaches taken towards trying to elucidate the event that happens in cancer cells that were exposed to platinum complexes. The experimental methods used to study the cellular interactions of platinum complexes are reviewed and the significance of the results obtained from such studies is discussed.

AB - This manuscript represents a critical review of selected topics relating to the cellular interactions of platinum anticancer drugs. The intent is not to provide a comprehensive summary of all the work described in the literature but to raise questions and cast doubts about selected topics regarding the approaches taken towards trying to elucidate the event that happens in cancer cells that were exposed to platinum complexes. The experimental methods used to study the cellular interactions of platinum complexes are reviewed and the significance of the results obtained from such studies is discussed.

KW - Cellular interactions

KW - Platinun anti cancer agents

UR - http://www.scopus.com/inward/record.url?scp=84868580018&partnerID=8YFLogxK

U2 - 10.1016/j.ica.2012.07.013

DO - 10.1016/j.ica.2012.07.013

M3 - Review article

AN - SCOPUS:84868580018

SN - 0020-1693

VL - 393

SP - 75

EP - 83

JO - Inorganica Chimica Acta

JF - Inorganica Chimica Acta

ER -

Cellular interactions of platinum drugs

Abstract

Bibliographical note

Keywords

UN SDGs

Access to Document

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