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Cellular interactions of platinum drugs

Research output: Contribution to journalReview articlepeer-review

67 Scopus citations

Abstract

This manuscript represents a critical review of selected topics relating to the cellular interactions of platinum anticancer drugs. The intent is not to provide a comprehensive summary of all the work described in the literature but to raise questions and cast doubts about selected topics regarding the approaches taken towards trying to elucidate the event that happens in cancer cells that were exposed to platinum complexes. The experimental methods used to study the cellular interactions of platinum complexes are reviewed and the significance of the results obtained from such studies is discussed.

Original languageEnglish
Pages (from-to)75-83
Number of pages9
JournalInorganica Chimica Acta
Volume393
DOIs
StatePublished - 1 Dec 2012

Bibliographical note

Funding Information:
D.G. thanks the Israel Science Foundation for financial support (Grant 1332/10 ).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Cellular interactions
  • Platinun anti cancer agents

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