TY - JOUR
T1 - Central auditory tests and auditory nerve-brainstem evoked responses in multiple sclerosis
AU - Matathias, O.
AU - Sohmer, H.
AU - Biton, V.
PY - 1985
Y1 - 1985
N2 - In 43 multiple sclerosis (MS) patients and an equal number of age- and sex-matched normal controls, auditory nerve-brainstem evoked responses (ABR), audiometric tests, central auditory tests (CAT) and clinical-neurological examinations were conducted. The CAT included rapid alternating speech perception, masking level differences to tones and to words and lateralization based on interaural time and intensity differences. The results in the MS group on the ABR and each of the CAT differed significantly from those in the control group. The ABR results and the lateralization test results were each abnormal in 50% of the MS patients. The ABR, CAT and clinical examination results were ail mutually correlated. These findings are probably related to the fact that the demyelination in MS induces a decrease in impulse velocity, to temporal dispersion and to desynchrony of impulses in groups of affected axons and to the fact that the ABR and the CAT tests chosen are dependent on synchronous impulse firing and on the precise timing of the arrival of impulses from each ear at some brain centre. These tests may therefore contribute to neurological and to audiological diagnosis.
AB - In 43 multiple sclerosis (MS) patients and an equal number of age- and sex-matched normal controls, auditory nerve-brainstem evoked responses (ABR), audiometric tests, central auditory tests (CAT) and clinical-neurological examinations were conducted. The CAT included rapid alternating speech perception, masking level differences to tones and to words and lateralization based on interaural time and intensity differences. The results in the MS group on the ABR and each of the CAT differed significantly from those in the control group. The ABR results and the lateralization test results were each abnormal in 50% of the MS patients. The ABR, CAT and clinical examination results were ail mutually correlated. These findings are probably related to the fact that the demyelination in MS induces a decrease in impulse velocity, to temporal dispersion and to desynchrony of impulses in groups of affected axons and to the fact that the ABR and the CAT tests chosen are dependent on synchronous impulse firing and on the precise timing of the arrival of impulses from each ear at some brain centre. These tests may therefore contribute to neurological and to audiological diagnosis.
KW - Binaural fusion
KW - Lateralization
KW - Masking level difference (MLD)
KW - Neurological
KW - Rapid alternating speech perception (RASP)
UR - http://www.scopus.com/inward/record.url?scp=0021867223&partnerID=8YFLogxK
U2 - 10.3109/00016488509108925
DO - 10.3109/00016488509108925
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C2 - 4013726
AN - SCOPUS:0021867223
SN - 0001-6489
VL - 99
SP - 369
EP - 376
JO - Acta Oto-Laryngologica
JF - Acta Oto-Laryngologica
IS - 3-4
ER -