Central diabetes insipidus in five cats: Clinical presentation, diagnosis and oral desmopressin therapy

Itamar Aroch*, Michal Mazaki-Tovi, Oved Shemesh, Havi Sarfaty, Gilad Segev

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

Five cases of central diabetes insipidus (CDI) in domestic shorthair cats are described. All cats were under 3 years of age at the onset of clinical signs, and outdoor or outdoor/indoor cats, in which a prior trauma was either present or possible. The history included polydipsia and polyuria, and physical examination abnormalities included urinary bladder distention and dehydration. All cats had hyposthenuria with a urine specific gravity between 1.003 and 1.006. The diagnosis was confirmed by an observed inability to concentrate urine during a water deprivation test or compatible serum osmolality, followed by an increase in urine concentration after desmopressin administration. All cats in this report were treated successfully with oral desmopressin. The dose (25-50 μg q8-12h) and the response to therapy were variable. Oral desmopressin administration may serve as an effective alternative route for cat owners who find the conjunctival or nasal application of the solution an inconvenient mode of therapy.

Original languageAmerican English
Pages (from-to)333-339
Number of pages7
JournalJournal of Feline Medicine and Surgery
Volume7
Issue number6
DOIs
StatePublished - Dec 2005

Fingerprint

Dive into the research topics of 'Central diabetes insipidus in five cats: Clinical presentation, diagnosis and oral desmopressin therapy'. Together they form a unique fingerprint.

Cite this