Central tyramine prevents hypertension in uninephrectomized DOCA-saline treated rats

B. Shalita, S. Dikstein*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Prevention of high blood pressure in uninephrectomized, DOCA-saline treated rats was observed after treatment with central tyramine precursors. We suggest that the high blood pressure is either due to relative lack of tyrosine, which might be caused by the hyperactivity of tyrosine hydroxylase, or to hypoactivity of the decarboxylase: in both cases the result is diminished tyramine synthesis.

Original languageEnglish
Pages (from-to)1430-1431
Number of pages2
JournalExperientia
Volume33
Issue number11
DOIs
StatePublished - Nov 1977

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