Chagosensine, a New Chlorinated Macrolide from the Red Sea Sponge Leucetta chagosensis

Tomáš Řezanka*, Lumír Hanuš, Valery M. Dembitsky

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Chagosensine, a sixteen-membered chlorinated macrolide, was isolated from the Red Sea calcareous sponge Leucetta chagosensis. Its structure was elucidated mainly on the basis of NMR spectroscopic data. The relative and absolute configurations were determined by analysis of 1H and 13C NMR, NOESY, and CD data, by the modified Mosher's method, and by using degradation products.

Original languageEnglish
Pages (from-to)4073-4079
Number of pages7
JournalEuropean Journal of Organic Chemistry
Issue number20
DOIs
StatePublished - 17 Oct 2003

Keywords

  • Chagosensine
  • Natural products
  • Red Sea sponge Leucetta chagosensis
  • Sixteen-membered chlorinated macrolide

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