Chagosensine, a New Chlorinated Macrolide from the Red Sea Sponge Leucetta chagosensis

Tomáš Řezanka; Lumír Hanuš; Valery M. Dembitsky

doi:10.1002/ejoc.200300240

Chagosensine, a New Chlorinated Macrolide from the Red Sea Sponge Leucetta chagosensis

Tomáš Řezanka^*
, Lumír Hanuš
, Valery M. Dembitsky

^*Corresponding author for this work

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Chagosensine, a sixteen-membered chlorinated macrolide, was isolated from the Red Sea calcareous sponge Leucetta chagosensis. Its structure was elucidated mainly on the basis of NMR spectroscopic data. The relative and absolute configurations were determined by analysis of ¹H and ¹³C NMR, NOESY, and CD data, by the modified Mosher's method, and by using degradation products.

Original language	English
Pages (from-to)	4073-4079
Number of pages	7
Journal	European Journal of Organic Chemistry
Issue number	20
DOIs	https://doi.org/10.1002/ejoc.200300240
State	Published - 17 Oct 2003

Keywords

Chagosensine
Natural products
Red Sea sponge Leucetta chagosensis
Sixteen-membered chlorinated macrolide

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10.1002/ejoc.200300240

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abstract = "Chagosensine, a sixteen-membered chlorinated macrolide, was isolated from the Red Sea calcareous sponge Leucetta chagosensis. Its structure was elucidated mainly on the basis of NMR spectroscopic data. The relative and absolute configurations were determined by analysis of 1H and 13C NMR, NOESY, and CD data, by the modified Mosher's method, and by using degradation products.",

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AU - Hanuš, Lumír

AU - Dembitsky, Valery M.

PY - 2003/10/17

Y1 - 2003/10/17

N2 - Chagosensine, a sixteen-membered chlorinated macrolide, was isolated from the Red Sea calcareous sponge Leucetta chagosensis. Its structure was elucidated mainly on the basis of NMR spectroscopic data. The relative and absolute configurations were determined by analysis of 1H and 13C NMR, NOESY, and CD data, by the modified Mosher's method, and by using degradation products.

AB - Chagosensine, a sixteen-membered chlorinated macrolide, was isolated from the Red Sea calcareous sponge Leucetta chagosensis. Its structure was elucidated mainly on the basis of NMR spectroscopic data. The relative and absolute configurations were determined by analysis of 1H and 13C NMR, NOESY, and CD data, by the modified Mosher's method, and by using degradation products.

KW - Chagosensine

KW - Natural products

KW - Red Sea sponge Leucetta chagosensis

KW - Sixteen-membered chlorinated macrolide

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JF - European Journal of Organic Chemistry

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ER -

Chagosensine, a New Chlorinated Macrolide from the Red Sea Sponge Leucetta chagosensis

Abstract

Keywords

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