Changes in aac(6′)-Ib-cr prevalence and fluoroquinolone resistance in nosocomial isolates of escherichia coli collected from 1991 through 2005

Gabriela Warburg, Maya Korem, Ari Robicsek, Dalia Engelstein, Allon E. Moses, Colin Block, Jacob Strahilevitz*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Clinical isolates of Escherichia coli collected from 1991 through 2005 at a tertiary-care center were studied for qnr and aac (6')-Ib-cr genes. Isolates bearing aac(6′)-Ib-cr emerged in 1998, coinciding with an increase in ciprofloxacin resistance. The presence of aac (6')-Ib-cr was multiclonal and was associated with the presence of extended-spectrum β-lactamases.

Original languageAmerican English
Pages (from-to)1268-1270
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume53
Issue number3
DOIs
StatePublished - Mar 2009
Externally publishedYes

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