Changes in aac(6′)-Ib-cr prevalence and fluoroquinolone resistance in nosocomial isolates of escherichia coli collected from 1991 through 2005

Gabriela Warburg; Maya Korem; Ari Robicsek; Dalia Engelstein; Allon E. Moses; Colin Block; Jacob Strahilevitz

doi:10.1128/AAC.01300-08

Changes in aac(6′)-Ib-cr prevalence and fluoroquinolone resistance in nosocomial isolates of escherichia coli collected from 1991 through 2005

Gabriela Warburg, Maya Korem, Ari Robicsek, Dalia Engelstein, Allon E. Moses, Colin Block, Jacob Strahilevitz^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Clinical isolates of Escherichia coli collected from 1991 through 2005 at a tertiary-care center were studied for qnr and aac (6')-Ib-cr genes. Isolates bearing aac(6′)-Ib-cr emerged in 1998, coinciding with an increase in ciprofloxacin resistance. The presence of aac (6')-Ib-cr was multiclonal and was associated with the presence of extended-spectrum β-lactamases.

Original language	English
Pages (from-to)	1268-1270
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	53
Issue number	3
DOIs	https://doi.org/10.1128/AAC.01300-08
State	Published - Mar 2009
Externally published	Yes

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title = "Changes in aac(6′)-Ib-cr prevalence and fluoroquinolone resistance in nosocomial isolates of escherichia coli collected from 1991 through 2005",

abstract = "Clinical isolates of Escherichia coli collected from 1991 through 2005 at a tertiary-care center were studied for qnr and aac (6')-Ib-cr genes. Isolates bearing aac(6′)-Ib-cr emerged in 1998, coinciding with an increase in ciprofloxacin resistance. The presence of aac (6')-Ib-cr was multiclonal and was associated with the presence of extended-spectrum β-lactamases.",

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AU - Robicsek, Ari

AU - Engelstein, Dalia

AU - Moses, Allon E.

AU - Block, Colin

AU - Strahilevitz, Jacob

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AB - Clinical isolates of Escherichia coli collected from 1991 through 2005 at a tertiary-care center were studied for qnr and aac (6')-Ib-cr genes. Isolates bearing aac(6′)-Ib-cr emerged in 1998, coinciding with an increase in ciprofloxacin resistance. The presence of aac (6')-Ib-cr was multiclonal and was associated with the presence of extended-spectrum β-lactamases.

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ER -

Changes in aac(6′)-Ib-cr prevalence and fluoroquinolone resistance in nosocomial isolates of escherichia coli collected from 1991 through 2005

Abstract

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