Changes in qnr prevalence and fluoroquinolone resistance in clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 to 2005

Jacob Strahilevitz; Dalia Engelstein; Amos Adler; Violeta Temper; Allon E. Moses; Colin Block; Ari Robicsek

doi:10.1128/AAC.00256-07

Changes in qnr prevalence and fluoroquinolone resistance in clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 to 2005

Jacob Strahilevitz^*
, Dalia Engelstein
, Amos Adler
, Violeta Temper
, Allon E. Moses
, Colin Block
, Ari Robicsek

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

Clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 through 2005 at a tertiary care center were studied for qnr genes. Isolates bearing these genes emerged in the mid-1990s, coinciding with the time of a rapid increase in fluoroquinolone resistance. Sixty percent of these isolates were ciprofloxacin susceptible by CLSI breakpoints.

Original language	English
Pages (from-to)	3001-3003
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	51
Issue number	8
DOIs	https://doi.org/10.1128/AAC.00256-07
State	Published - Aug 2007
Externally published	Yes

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SDG 3 Good Health and Well-being

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10.1128/AAC.00256-07

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title = "Changes in qnr prevalence and fluoroquinolone resistance in clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 to 2005",

abstract = "Clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 through 2005 at a tertiary care center were studied for qnr genes. Isolates bearing these genes emerged in the mid-1990s, coinciding with the time of a rapid increase in fluoroquinolone resistance. Sixty percent of these isolates were ciprofloxacin susceptible by CLSI breakpoints.",

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AU - Strahilevitz, Jacob

AU - Engelstein, Dalia

AU - Adler, Amos

AU - Temper, Violeta

AU - Moses, Allon E.

AU - Block, Colin

AU - Robicsek, Ari

PY - 2007/8

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AB - Clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 through 2005 at a tertiary care center were studied for qnr genes. Isolates bearing these genes emerged in the mid-1990s, coinciding with the time of a rapid increase in fluoroquinolone resistance. Sixty percent of these isolates were ciprofloxacin susceptible by CLSI breakpoints.

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ER -

Changes in qnr prevalence and fluoroquinolone resistance in clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 to 2005

Abstract

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