Channels, Carriers, and Pumps: An Introduction to Membrane Transport

Wilfred D. Stein*, Thomas Litman

*Corresponding author for this work

Research output: Book/ReportBookpeer-review

36 Scopus citations

Abstract

An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered.

Original languageEnglish
PublisherElsevier Inc.
Number of pages406
ISBN (Electronic)9780124165830
ISBN (Print)9780124165793
DOIs
StatePublished - 17 Dec 2014

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc. All rights reserved.

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