Characteristic folding pattern of polytene chromosomes in Drosophila salivary gland nuclei

David Mathog; Mark Hochstrasser; Yosef Gruenbaum; Harald Saumweber; John Sedat

doi:10.1038/308414a0

Characteristic folding pattern of polytene chromosomes in Drosophila salivary gland nuclei

David Mathog^*, Mark Hochstrasser, Yosef Gruenbaum, Harald Saumweber, John Sedat

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

146 Scopus citations

Abstract

A computer-based system for recording and analysing light microscope images, combined with classical cytogenetic analysis, has revealed the spatial organization of the giant chromosomes of Drosophila salivary gland cells. Each polytene chromosome arm folds up in a characteristic way, contacts the nuclear surface at specific sites and is topologically isolated from all other arms.

Original language	English
Pages (from-to)	414-421
Number of pages	8
Journal	Nature
Volume	308
Issue number	5958
DOIs	https://doi.org/10.1038/308414a0
State	Published - 1984
Externally published	Yes

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abstract = "A computer-based system for recording and analysing light microscope images, combined with classical cytogenetic analysis, has revealed the spatial organization of the giant chromosomes of Drosophila salivary gland cells. Each polytene chromosome arm folds up in a characteristic way, contacts the nuclear surface at specific sites and is topologically isolated from all other arms.",

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AU - Sedat, John

PY - 1984

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Characteristic folding pattern of polytene chromosomes in Drosophila salivary gland nuclei

Abstract

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