Characteristic Surface Morphology of Human and Murine Myeloma Cells: a Scanning and Transmission Electron Microscopic Study

Aaron Polliack*, Kenneth Nilsson, Reuven Laskov, Peter Biberfeld

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Summary. Cells from cultured human and murine myeloma cell lines and circulating leukacmic plasma cells from four patients with generalized myeloma were studied by transmission and scanning electron microscopy and time‐lapse cinematography. Both circulating and cultured cells exhibited consistent surface architectures and varying numbers of prominent blebs of different sizes were seen, in addition to microvilli. The presence of surface blebs appears to be a characteristic feature for secreting and non‐secreting myeloma cells.

Original languageEnglish
Pages (from-to)25-32
Number of pages8
JournalBritish Journal of Haematology
Volume39
Issue number1
DOIs
StatePublished - May 1978

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