Chemical Synthesis of Selenoproteins

Rebecca N. Dardashti; Reem Ghadir; Hiba Ghareeb; Orit Weil-Ktorza; Norman Metanis

doi:10.1002/9783527823567.ch17

Chemical Synthesis of Selenoproteins

Rebecca N. Dardashti, Reem Ghadir, Hiba Ghareeb, Orit Weil-Ktorza, Norman Metanis

Institute of Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Chemical protein synthesis is a great approach for accessing challenging proteins, such as post-translationally modified proteins, proteins with unnatural amino acids, and proteins with rare natural amino acids such as selenoproteins. In this book chapter we will discuss the recent advances in the chemical synthesis of selenoproteins, as well as the unique chemistry of selenopeptides and selenoproteins.

Original language	English
Title of host publication	Total Chemical Synthesis of Proteins
Publisher	wiley
Pages	463-488
Number of pages	26
ISBN (Electronic)	9783527823567
ISBN (Print)	9783527346608
DOIs	https://doi.org/10.1002/9783527823567.ch17
State	Published - 1 Jan 2021

Bibliographical note

Publisher Copyright:
© 2021 WILEY-VCH GmbH. Published 2021 by WILEY-VCH GmbH.

Keywords

Selenocysteine
chemical protein synthesis
chemoselective reactions
native chemical ligation
selenopeptides
selenoproteins

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10.1002/9783527823567.ch17

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Chemical Synthesis of Selenoproteins

Abstract

Bibliographical note

Keywords

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