TY - JOUR
T1 - Chemistry of 2-bromo-2-methylpropanamides. Synthesis and solvolytic behaviour of oxazolidinones and spiro-oxazolidinones
AU - Scrimin, Paolo
AU - Cavicchioni, Giorgio
AU - D'Angeli, Ferruccio
AU - Goldblum, Amiram
AU - Maran, Flavio
PY - 1988
Y1 - 1988
N2 - The base-promoted reaction of 2-bromo-2-methylpropanamides (1) with 5-, 6-, and 7-membered lactams (2) affords spiro-oxazolidinones (3). The latter compounds are hydrolysed under acidic conditions to yield the ω-aminoester amides (7). The solvolytic behaviour of some monocyclic oxazolidinones obtained upon reaction of common amides with 2-bromoamides (1) is also reported.
AB - The base-promoted reaction of 2-bromo-2-methylpropanamides (1) with 5-, 6-, and 7-membered lactams (2) affords spiro-oxazolidinones (3). The latter compounds are hydrolysed under acidic conditions to yield the ω-aminoester amides (7). The solvolytic behaviour of some monocyclic oxazolidinones obtained upon reaction of common amides with 2-bromoamides (1) is also reported.
UR - http://www.scopus.com/inward/record.url?scp=0344915138&partnerID=8YFLogxK
U2 - 10.1039/p19880000043
DO - 10.1039/p19880000043
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AN - SCOPUS:0344915138
SN - 1472-7781
SP - 43
EP - 47
JO - Journal of the Chemical Society, Perkin Transactions 1
JF - Journal of the Chemical Society, Perkin Transactions 1
IS - 1
ER -