Chorionic villus sampling prior to pregnancy termination, a tool for forensic paternity testing

Ayeleth Reshef; Paul Brauner; Moshe Shpitzen; Nira Gallili; Assa Marbach; Uzi Motro; Esther Shmueli; Vardiela Meiner

doi:10.1520/jfs12044j

Chorionic villus sampling prior to pregnancy termination, a tool for forensic paternity testing

Ayeleth Reshef^*, Paul Brauner, Moshe Shpitzen, Nira Gallili, Assa Marbach, Uzi Motro, Esther Shmueli, Vardiela Meiner

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Chorionic villus sampling (CVS), prior to pregnancy termination (pre- termination CVS), is suggested as a tool for forensic paternity testing. Unlike the abortion material, which consists of ruptured tissues of fetal and maternal origin, extra-embryonic membranes obtained through CVS can provide an uncontaminated source of fetal tissue for genotyping. We discuss the possibility of confined placental mosaicism (CPM) and its implications on the polymerase chain reaction (PCR) based analyses of short tandem repeats (STRs) and the D1S80 loci.

Original language	English
Pages (from-to)	1065-1068
Number of pages	4
Journal	Journal of Forensic Sciences
Volume	44
Issue number	5
DOIs	https://doi.org/10.1520/jfs12044j
State	Published - Sep 1999

Keywords

CSF1PO
Chorionic villus sampling
Confined placental mosaicism
D1S80
Dna typing
F13AO1
F13B
FES/FPS
Forensic science
LPL
Paternity testing
Polymerase chain reaction
Short tandem repeats
THO1
TPOX
VWA

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10.1520/jfs12044j

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title = "Chorionic villus sampling prior to pregnancy termination, a tool for forensic paternity testing",

abstract = "Chorionic villus sampling (CVS), prior to pregnancy termination (pre- termination CVS), is suggested as a tool for forensic paternity testing. Unlike the abortion material, which consists of ruptured tissues of fetal and maternal origin, extra-embryonic membranes obtained through CVS can provide an uncontaminated source of fetal tissue for genotyping. We discuss the possibility of confined placental mosaicism (CPM) and its implications on the polymerase chain reaction (PCR) based analyses of short tandem repeats (STRs) and the D1S80 loci.",

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author = "Ayeleth Reshef and Paul Brauner and Moshe Shpitzen and Nira Gallili and Assa Marbach and Uzi Motro and Esther Shmueli and Vardiela Meiner",

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AU - Reshef, Ayeleth

AU - Brauner, Paul

AU - Shpitzen, Moshe

AU - Gallili, Nira

AU - Marbach, Assa

AU - Motro, Uzi

AU - Shmueli, Esther

AU - Meiner, Vardiela

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KW - Paternity testing

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KW - TPOX

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Chorionic villus sampling prior to pregnancy termination, a tool for forensic paternity testing

Abstract

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