Chromosomal distribution of genes coding for fast twitch skeletal muscle myosin light chains

Henryk Czosnek; Peter E. Barker; Frank H. Ruddle; Benoit Robert

doi:10.1007/BF01534719

Chromosomal distribution of genes coding for fast twitch skeletal muscle myosin light chains

Henryk Czosnek^*, Peter E. Barker, Frank H. Ruddle, Benoit Robert

^*Corresponding author for this work

Institute of Plant Sciences and Genetics in Agriculture

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The mouse fast twitch skeletal muscle myosin light chains are encoded by a multigene family which comprises the gene coding for the myosin light chain 2 (Myl_2f), and the gene coding for both myosin light chains 1 and 3 (Myl_1f/Myl_3f). In addition, a Myl_1f/Myl_3f-related pseudogene is present in the domestic mouse Mus musculus. The members of this gene family were assigned to chromosomes by molecular hybridization; using DNA extracted from a panel of cloned mouse-Chinese hamster somatic hybrid cells and specific DNA probes. The genes coding for the light chains of the myosin molecule are dispersed on several chromosomes, while genes coding for the heavy chain of myosin are located on a single, different chromosome.

Original language	English
Pages (from-to)	533-540
Number of pages	8
Journal	Somatic Cell and Molecular Genetics
Volume	11
Issue number	6
DOIs	https://doi.org/10.1007/BF01534719
State	Published - Nov 1985

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title = "Chromosomal distribution of genes coding for fast twitch skeletal muscle myosin light chains",

abstract = "The mouse fast twitch skeletal muscle myosin light chains are encoded by a multigene family which comprises the gene coding for the myosin light chain 2 (Myl2f), and the gene coding for both myosin light chains 1 and 3 (Myl1f/Myl3f). In addition, a Myl1f/Myl3f-related pseudogene is present in the domestic mouse Mus musculus. The members of this gene family were assigned to chromosomes by molecular hybridization; using DNA extracted from a panel of cloned mouse-Chinese hamster somatic hybrid cells and specific DNA probes. The genes coding for the light chains of the myosin molecule are dispersed on several chromosomes, while genes coding for the heavy chain of myosin are located on a single, different chromosome.",

author = "Henryk Czosnek and Barker, {Peter E.} and Ruddle, {Frank H.} and Benoit Robert",

year = "1985",

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doi = "10.1007/BF01534719",

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AU - Barker, Peter E.

AU - Ruddle, Frank H.

AU - Robert, Benoit

PY - 1985/11

Y1 - 1985/11

N2 - The mouse fast twitch skeletal muscle myosin light chains are encoded by a multigene family which comprises the gene coding for the myosin light chain 2 (Myl2f), and the gene coding for both myosin light chains 1 and 3 (Myl1f/Myl3f). In addition, a Myl1f/Myl3f-related pseudogene is present in the domestic mouse Mus musculus. The members of this gene family were assigned to chromosomes by molecular hybridization; using DNA extracted from a panel of cloned mouse-Chinese hamster somatic hybrid cells and specific DNA probes. The genes coding for the light chains of the myosin molecule are dispersed on several chromosomes, while genes coding for the heavy chain of myosin are located on a single, different chromosome.

AB - The mouse fast twitch skeletal muscle myosin light chains are encoded by a multigene family which comprises the gene coding for the myosin light chain 2 (Myl2f), and the gene coding for both myosin light chains 1 and 3 (Myl1f/Myl3f). In addition, a Myl1f/Myl3f-related pseudogene is present in the domestic mouse Mus musculus. The members of this gene family were assigned to chromosomes by molecular hybridization; using DNA extracted from a panel of cloned mouse-Chinese hamster somatic hybrid cells and specific DNA probes. The genes coding for the light chains of the myosin molecule are dispersed on several chromosomes, while genes coding for the heavy chain of myosin are located on a single, different chromosome.

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Chromosomal distribution of genes coding for fast twitch skeletal muscle myosin light chains

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