Clinical implications of E-cadherin associated hereditary diffuse gastric cancer

R. C. Fitzgerald; C. Caldas

doi:10.1136/gut.2003.022061

Clinical implications of E-cadherin associated hereditary diffuse gastric cancer

R. C. Fitzgerald^*
, C. Caldas

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

96 Scopus citations

Abstract

Approximately 1-3% of gastric cancers arise as a result of inherited gastric cancer predisposition syndromes. These may be of the diffuse or intestinal type. Linkage analysis has recently implicated E-cadherin mutations in an estimated 25% of families with an autosomal dominant predisposition to diffuse type gastric cancers. This subset of gastric cancer has been termed hereditary diffuse gastric cancer (HDGC).

Original language	English
Pages (from-to)	775-778
Number of pages	4
Journal	Gut
Volume	53
Issue number	6
DOIs	https://doi.org/10.1136/gut.2003.022061
State	Published - Jun 2004
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1136/gut.2003.022061

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title = "Clinical implications of E-cadherin associated hereditary diffuse gastric cancer",

abstract = "Approximately 1-3\% of gastric cancers arise as a result of inherited gastric cancer predisposition syndromes. These may be of the diffuse or intestinal type. Linkage analysis has recently implicated E-cadherin mutations in an estimated 25\% of families with an autosomal dominant predisposition to diffuse type gastric cancers. This subset of gastric cancer has been termed hereditary diffuse gastric cancer (HDGC).",

author = "Fitzgerald, \{R. C.\} and C. Caldas",

year = "2004",

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AU - Caldas, C.

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AB - Approximately 1-3% of gastric cancers arise as a result of inherited gastric cancer predisposition syndromes. These may be of the diffuse or intestinal type. Linkage analysis has recently implicated E-cadherin mutations in an estimated 25% of families with an autosomal dominant predisposition to diffuse type gastric cancers. This subset of gastric cancer has been termed hereditary diffuse gastric cancer (HDGC).

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JO - Gut

JF - Gut

IS - 6

ER -

Clinical implications of E-cadherin associated hereditary diffuse gastric cancer

Abstract

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