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Coherent activation of DNA tweezers: A "SET-RESET" logic system

  • Johann Elbaz*
  • , Michal Moshe
  • , Itamar Willner
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

151 Scopus citations

Abstract

Open sesame: Aptamer-substrate complexes activate the coherent operation of two tweezers that act as a "SET-RESET" logic system. Each tweezer cycles between a fluorescent open state and a closed quenched state (Q=quencher, F=fluorophore) when triggered by adenosine monophosphate (AMP) and adenosine deaminase (AD).

Original languageEnglish
Pages (from-to)3834-3837
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number21
DOIs
StatePublished - 11 May 2009

Keywords

  • Aptamers
  • DNA machinesl logic gates
  • Molecular devices
  • Tweezers

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