Antiphospholipid syndrome and cold agglutinin-mediated autoimmune hemolytic anemia are 2 distinct immune-mediated hematologic disorders. While no clear association exists between these 2 entities, complement activation is known to occur in both of them. Herein, we report a unique case of cold agglutinin hemolytic anemia in a patient with a known primary antiphospholipid syndrome.
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© 2021 The Author(s) Published by S. Karger AG, Basel.
- Antiphospholipid syndrome
- Cold agglutinin
- Complement activation
- Hemolytic anemia