Cold Agglutinin-Mediated Autoimmune Hemolytic Anemia in Association with Antiphospholipid Syndrome

Ram Gelman; Fadi Kharouf; Yuval Ishay; Alexander Gural

doi:10.1159/000516295

Cold Agglutinin-Mediated Autoimmune Hemolytic Anemia in Association with Antiphospholipid Syndrome

Ram Gelman^*, Fadi Kharouf, Yuval Ishay, Alexander Gural

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Antiphospholipid syndrome and cold agglutinin-mediated autoimmune hemolytic anemia are 2 distinct immune-mediated hematologic disorders. While no clear association exists between these 2 entities, complement activation is known to occur in both of them. Herein, we report a unique case of cold agglutinin hemolytic anemia in a patient with a known primary antiphospholipid syndrome.

Original language	English
Pages (from-to)	693-697
Number of pages	5
Journal	Acta Haematologica
Volume	144
Issue number	6
DOIs	https://doi.org/10.1159/000516295
State	Published - 1 Nov 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2021 The Author(s) Published by S. Karger AG, Basel.

Keywords

Antiphospholipid syndrome
Cold agglutinin
Complement activation
Hemolytic anemia

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10.1159/000516295

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abstract = "Antiphospholipid syndrome and cold agglutinin-mediated autoimmune hemolytic anemia are 2 distinct immune-mediated hematologic disorders. While no clear association exists between these 2 entities, complement activation is known to occur in both of them. Herein, we report a unique case of cold agglutinin hemolytic anemia in a patient with a known primary antiphospholipid syndrome.",

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AU - Gelman, Ram

AU - Kharouf, Fadi

AU - Ishay, Yuval

AU - Gural, Alexander

PY - 2021/11/1

Y1 - 2021/11/1

N2 - Antiphospholipid syndrome and cold agglutinin-mediated autoimmune hemolytic anemia are 2 distinct immune-mediated hematologic disorders. While no clear association exists between these 2 entities, complement activation is known to occur in both of them. Herein, we report a unique case of cold agglutinin hemolytic anemia in a patient with a known primary antiphospholipid syndrome.

AB - Antiphospholipid syndrome and cold agglutinin-mediated autoimmune hemolytic anemia are 2 distinct immune-mediated hematologic disorders. While no clear association exists between these 2 entities, complement activation is known to occur in both of them. Herein, we report a unique case of cold agglutinin hemolytic anemia in a patient with a known primary antiphospholipid syndrome.

KW - Antiphospholipid syndrome

KW - Cold agglutinin

KW - Complement activation

KW - Hemolytic anemia

UR - https://www.scopus.com/pages/publications/85107484398

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DO - 10.1159/000516295

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IS - 6

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Cold Agglutinin-Mediated Autoimmune Hemolytic Anemia in Association with Antiphospholipid Syndrome

Abstract

Bibliographical note

Keywords

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