Comparison of simultaneous splenic sample PCR with blood sample PCR for diagnosis and treatment of experimental Ehrlichia canis infection

Shimon Harrus; Martin Kenny; Limor Miara; Itzhak Aizenberg; Trevor Waner; Susan Shaw

doi:10.1128/AAC.48.11.4488-4490.2004

Comparison of simultaneous splenic sample PCR with blood sample PCR for diagnosis and treatment of experimental Ehrlichia canis infection

Shimon Harrus^*, Martin Kenny, Limor Miara, Itzhak Aizenberg, Trevor Waner, Susan Shaw

^*Corresponding author for this work

The Koret School of Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

89 Scopus citations

Abstract

This report presents evidence that dogs recover from acute canine monocytic ehrlichiosis (CME) after 16 days of doxycycline treatment (10 mg/kg of body weight every 24 h). Blood PCR was as valuable as splenic aspirate PCR for early diagnosis of acute CME. Splenic aspirate PCR was, however, superior to blood PCR for the evaluation of ehrlichial elimination.

Original language	American English
Pages (from-to)	4488-4490
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	48
Issue number	11
DOIs	https://doi.org/10.1128/AAC.48.11.4488-4490.2004
State	Published - Nov 2004

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10.1128/AAC.48.11.4488-4490.2004

Cite this

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title = "Comparison of simultaneous splenic sample PCR with blood sample PCR for diagnosis and treatment of experimental Ehrlichia canis infection",

abstract = "This report presents evidence that dogs recover from acute canine monocytic ehrlichiosis (CME) after 16 days of doxycycline treatment (10 mg/kg of body weight every 24 h). Blood PCR was as valuable as splenic aspirate PCR for early diagnosis of acute CME. Splenic aspirate PCR was, however, superior to blood PCR for the evaluation of ehrlichial elimination.",

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AU - Aizenberg, Itzhak

AU - Waner, Trevor

AU - Shaw, Susan

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AB - This report presents evidence that dogs recover from acute canine monocytic ehrlichiosis (CME) after 16 days of doxycycline treatment (10 mg/kg of body weight every 24 h). Blood PCR was as valuable as splenic aspirate PCR for early diagnosis of acute CME. Splenic aspirate PCR was, however, superior to blood PCR for the evaluation of ehrlichial elimination.

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ER -

Comparison of simultaneous splenic sample PCR with blood sample PCR for diagnosis and treatment of experimental Ehrlichia canis infection

Abstract

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