Complement Activation, Immunogenicity, and Immune Suppression as Potential Side Effects of Liposomes

Janos Szebeni*, Yechezkel Chezy Barenholz

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations
Original languageEnglish
Title of host publicationAdvances in Clinical Immunology, Medical Microbiology, COVID-19, and Big Data
PublisherJenny Stanford Publishing
Pages55-75
Number of pages21
ISBN (Electronic)9781000400816
ISBN (Print)9789814877848
StatePublished - 1 Jan 2021

Keywords

  • accelerated blood clearance
  • acute hypersensitivity reactions
  • adjuvant
  • anaphylatoxins
  • antigenicity
  • approved liposomal drugs
  • basophil leukocyte activation-based allergenicity assays
  • C activation-related pseudoallergy
  • complement activation
  • Doxil
  • immune suppression
  • immunogenicity
  • Lipinsky box
  • liposomal doxorubicin
  • liposomology
  • normal human sera
  • PEGylated nanoliposome
  • reactogenicity
  • reticuloendothelial system

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