Computer analysis of factors influencing the appearance of aseptic necrosis in patients with SLE

J. Dimant, E. M. Ginzler, H. S. Diamond, M. Schlesinger, C. T. Marino, M. Weiner, D. Kaplan

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

A computer analysis of 234 patients with SLE followed for an average of 31 months revealed 22 patients with aseptic necrosis of bone (AN) (9%), with projected frequency approaching 30% at 10-15 years of follow-up. Most patients developed AN between four and seven years after diagnosis of SLE. When compared to all other patients with SLE and no AN or to three computer-selected groups matched by age of SLE diagnosis, duration of disease, or cumulative corticosteroid dose, AN did not correlate with any of the preliminary ARA criteria, total number of criteria fulfilled, renal disease, skin vasculitis, or disease activity. Although all patients received corticosteroid therapy prior to development of AN, no correlation was found with duration, peak dose, or cumulative dose of corticosteroid therapy.

Original languageEnglish
Pages (from-to)136-141
Number of pages6
JournalUnknown Journal
Volume5
Issue number2
StatePublished - 1978

Fingerprint

Dive into the research topics of 'Computer analysis of factors influencing the appearance of aseptic necrosis in patients with SLE'. Together they form a unique fingerprint.

Cite this