Concentrations of ionized and total magnesium and calcium in healthy horses: Effects of age, pregnancy, lactation, pH and sample type

Dalia Berlin*, Itamar Aroch

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

Magnesium (Mg) and calcium (Ca) are the main divalent cations in the body. The free ionized fraction is the physiologically active form of both Mg and Ca. As ion-selective-electrode (ISE) analyzers are becoming widely used in veterinary practice it will be useful to establish reference intervals for horses. In the present study, reference intervals were established for ionized, total and the ratio of the ionized to total Mg and Ca concentrations in four horse groups: adults, neonatal foals, and pregnant and lactating mares, as well as in three sample types, whole blood, plasma and serum, using an ISE-analyzer. Sample pH effect was assessed. Concentration differences in both total and ionized cations were recorded for some measures between horse groups and different sample types. The most significant differences were recorded between neonatal foals and other groups. These results demonstrate the need to use specific reference intervals for horses of different physiologic status and in specific sample types.

Original languageAmerican English
Pages (from-to)305-311
Number of pages7
JournalVeterinary Journal
Volume181
Issue number3
DOIs
StatePublished - Sep 2009

Keywords

  • Equine
  • Ion-selective-electrode
  • Plasma
  • Serum
  • Whole blood

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