Conformational Dynamics Associated with Photoswitchable Binding of Spiropyran-Modified Concanavalin A

Eran Zahavy, Shai Rubin, Itamar Willner

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Spiropyran modified concanavalin A, Con. A, reveals photoregulated binding towards monosaccharides. The association constants of the substrate towards the spiro-Con. A and the kinetics of the association processes are photostimulated. These photostimulated properties are originated from a structural perturbation of the protein upon photoisomerization of spiro-Con. A to the zwitterionic Con. A. Time resolved light scattering reveals that the structural change of the protein involves a shrinkage.

Original languageEnglish
Pages (from-to)195-199
Number of pages5
JournalMolecular Crystals and Liquid Crystals
Volume246
Issue number1
DOIs
StatePublished - 1 May 1994

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