TY - JOUR
T1 - Continuous chromosomal instability in human pluripotent stem cells–the role of DNA replication
AU - Lamm, Noa
AU - Kerem, Batsheva
N1 - Publisher Copyright:
© 2016, © 2016 Taylor & Francis Group, LLC.
PY - 2016/7/3
Y1 - 2016/7/3
N2 - Human pluripotent stem cells (hPSCs) frequently acquire chromosomal aberrations, including aneuploidy, during culture. Recently, we identified a replication stress-based mechanism leading to ongoing chromosomal instability in aneuploid hPSCs that may also operate during the initiation of instability in diploid cells.
AB - Human pluripotent stem cells (hPSCs) frequently acquire chromosomal aberrations, including aneuploidy, during culture. Recently, we identified a replication stress-based mechanism leading to ongoing chromosomal instability in aneuploid hPSCs that may also operate during the initiation of instability in diploid cells.
UR - http://www.scopus.com/inward/record.url?scp=85050752499&partnerID=8YFLogxK
U2 - 10.1080/23723556.2016.1183743
DO - 10.1080/23723556.2016.1183743
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AN - SCOPUS:85050752499
SN - 2372-3556
VL - 3
JO - Molecular and Cellular Oncology
JF - Molecular and Cellular Oncology
IS - 4
M1 - e1183743
ER -