Abstract
Human pluripotent stem cells (hPSCs) frequently acquire chromosomal aberrations, including aneuploidy, during culture. Recently, we identified a replication stress-based mechanism leading to ongoing chromosomal instability in aneuploid hPSCs that may also operate during the initiation of instability in diploid cells.
| Original language | English |
|---|---|
| Article number | e1183743 |
| Journal | Molecular and Cellular Oncology |
| Volume | 3 |
| Issue number | 4 |
| DOIs | |
| State | Published - 3 Jul 2016 |
Bibliographical note
Publisher Copyright:© 2016, © 2016 Taylor & Francis Group, LLC.
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